Professor Robert Baxter
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Professor and Director, Kolling Institute of Medical Research
E25 - Royal North Shore Hospital
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Current national competitive grants*
2010
Protein discovery for breast cancer diagnosis
Baxter R, Moore K, Marsh D, Boyle F, McCarthy N
NHMRC Project Grant ($397,125 over 3 years)
2009
How IGFBP-3 improves cancer cell responsiveness to DNA-damaging therapies
Baxter R
ARC Discovery Project ($480,000 over 3 years)
2007
Breast Cancer Tissue Bank
Clarke C, Baxter R, Bilous M, Boyages J, Carpenter J, Forbes J, Friedlander M, Harnett P, Kefford R, Marsh D, Morey A, Scott R, Spigelman A, Sutherland R, Balleine R
National Breast Cancer Foundation Project Grants ($1,455,090 over 5 years)
Novel regulators of fat cell differentiation
Twigg S, McLennan S, Baxter R
NHMRC Project Grant ($428,250 over 3 years)
Proteomic screening for apoptotic markers in cancer
Baxter R, Leong S, Christopherson R
NHMRC Project Grant ($511,500 over 3 years)
Proteolysis of binding protein complexes regulates IGF bioavailability
Firth S, Baxter R
ARC Discovery Projects ($234,000 over 3 years)
* Grants administered through the University of Sydney
Publications
2009
Chung, L., Nelson, A., Ho, K., Baxter, R. Proteomic profiling of growth hormone responsive proteins in human peripheral blood leukocytes. The Journal of clinical endocrinology and metabolism. 2009; 94:3038-43. [Abstract]
Chung, L., Baxter, R. Detection of growth hormone responsive proteins using SELDI-TOF mass spectrometry. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 2009; 19:383-7. [Abstract]
Gosby, A., Stanton, L., Maloney, C., Thompson, M., Briody, J., Baxter, R., Bryson, J., Denyer, G., Caterson, I. Postnatal nutrition alters body composition in adult offspring exposed to maternal protein restriction. The British journal of nutrition. 2009; 101:1878-84. [Abstract]
Chan, S., Schedlich, L., Twigg, S., Baxter, R. Inhibition of adipocyte differentiation by insulin-like growth factor-binding protein-3. American Journal of Physiology: Endocrinology and Metabolism. 2009; 296:E654-E663. [Abstract]
2008
Nguyen, T., Nelson, A., Howe, C., Seibel, M., Baxter, R., Handelsman, D., Kazlauskas, R., Ho, K. Within-Subject Variability and Analytic Imprecision of Insulin-Like Growth Factor Axis and Collagen Markers: Implications for Clinical Diagnosis and Doping Tests. Clinical chemistry. 2008; 54:1268-76. [Abstract]
Nelson, A., Meinhardt, U., Hansen, J., Walker, I., Stone, G., Howe, C., Leung, K., Seibel, M., Baxter, R., Handelsman, D., Kazlauskas, R., Ho, K. Pharmacodynamics of GH abuse biomarkers and the influence of gender and testosterone: a randomized double-blind placebo-controlled study in young recreational athletes. The Journal of clinical endocrinology and metabolism. 2008; 93:2213-22. [Abstract]
Marsh, D., Trahair, T., Martin, J., Chee, W., Walker, J., Kirk, E., Baxter, R., Marshall, G. Rapamycin treatment for a child with germline PTEN mutation. Nature clinical practice. Oncology. 2008; 5:357-61. [Abstract]
Chuang, S., Patton, K., Schafernak, K., Papavero, V., Lin, F., Baxter, R., Teh, B., Yang, X. Over expression of insulin-like growth factor binding protein 3 in clear cell renal cell carcinoma. The Journal of Urology. 2008; 179:445-449. [Abstract]
Baxter, R. Insulin-like Growth Factors and Tumor Hypoglycemia. In: Clinical Endocrine Oncology. United States: Wiley-Blackwell 2008. p. 576-581.
2007
Schedlich, L., Muthukaruppan, A., O'han, M., Baxter, R. Insulin-like growth factor binding protein-5 interacts with the vitamin D receptor and modulates the Vitamin D response in osteoblasts. Molecular endocrinology (Baltimore, Md.). 2007; 21:2378-90. [Abstract]
Schedlich, L., Graham, L., O'han, M., Muthukaruppan, A., Yan, X., Firth, S., Baxter, R. Molecular basis of the interaction between IGFBP-3 and retinoid X receptor: Role in modulation of RAR-signaling. Archives of biochemistry and biophysics. 2007; 465:359-69. [Abstract]
Scarlett, C., Samra, J., Xue, A., Baxter, R., Smith, R. Classification of pancreatic cystic lesions using seldi-tof mass spectrometry. ANZ journal of surgery. 2007; 77:648-653. [Abstract]
Graham, M., Kilby, D., Firth, S., Robinson, P., Baxter, R. The in vivo phosphorylation and glycosylation of human insulin-like growth factor binding protein-5. Molecular & cellular proteomics : MCP. 2007; 6:1392-405. [Abstract]
Martin, J., Baxter, R. Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway. Endocrinology. 2007; 148:2532-2541. [Abstract]
Baxter, R., Smith, R., Scarlett, C., Xue, A., Butturini, G., Scarpa, A. Hp07 proteomic identification of serum markers of pancreatic adenocarcinoma using seldi-tof ms. ANZ journal of surgery. 2007; 77:A41-A41. [Abstract]
Leong, S., Christopherson, R., Baxter, R. Profiling of Apoptotic Changes in Human Breast Cancer Cells Using SELDI-TOF Mass Spectrometry. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2007; 20:579-90. [Abstract]
2006
Yan, X., Baxter, R., Perbal, B., Firth, S. The aminoterminal insulin-like growth factor (IGF) binding domain of IGF binding protein-3 cannot be functionally substituted by the structurally homologous domain of CCN3. Endocrinology. 2006; 147:5268-74. [Abstract]
Nelson, A., Howe, C., Nguyen, T., Leung, K., Trout, G., Seibel, M., Baxter, R., Handelsman, D., Kazlauskas, R., Ho, K. Influence of demographic factors and sport type on growth hormone-responsive markers in elite athletes. The Journal of clinical endocrinology and metabolism. 2006; 91:4424-32. [Abstract]
Scarlett, C., Saxby, A., Nielsen, A., Bell, C., Samra, J., Hugh, T., Baxter, R., Smith, R. Proteomic profiling of cholangiocarcinoma: Diagnostic potential of SELDI-TOF MS in malignant bile duct stricture. Hepatology (Baltimore, Md.). 2006; 44:658-66. [Abstract]
Scarlett, C., Smith, R., Saxby, A., Nielsen, A., Samra, J., Wilson, S., Baxter, R. Proteomic classification of pancreatic adenocarcinoma tissue using protein chip technology. Gastroenterology. 2006; 130:1670-8. [Abstract]
Santer, F., Bacher, N., Moser, B., Morandell, D., Ressler, S., Firth, S., Spoden, G., Sergi, C., Baxter, R., Jansen-Dürr, P., Zwerschke, W. Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis. Cancer research. 2006; 66:3024-33. [Abstract]
Moscova, M., Marsh, D., Baxter, R. Protein chip discovery of secreted proteins regulated by the phosphatidylinositol 3-kinase pathway in ovarian cancer cell lines. Cancer research. 2006; 66:1376-83. [Abstract]
Chung, L., Clifford, D., Buckley, M., Baxter, R. Novel biomarkers of human growth hormone action from serum proteomic profiling using protein chip mass spectrometry. The Journal of clinical endocrinology and metabolism. 2006; 91:671-7. [Abstract]
2005
Moscova, M., Marsh, D., Baxter, R. Identification of Cytokines regulated by phosphatidylinositol-3 kinase in ovarian cancer. Clinical Cancer Research. 2005; 11:8977S-8977S. [Abstract]
Chan, S., Twigg, S., Firth, S., Baxter, R. Insulin-like growth factor binding protein-3 leads to insulin resistance in adipocytes. The Journal of clinical endocrinology and metabolism. 2005; 90:6588-95. [Abstract]
Sevette, A., Smith, R., Aslani, A., Kee, A., Hansen, R., Barratt, S., Baxter, R. Does growth hormone allow more efficient nitrogen sparing in postoperative patients requiring parenteral nutrition? A double-blind, placebo-controlled randomised trial. Clinical nutrition (Edinburgh, Lothian). 2005; 24:943-55. [Abstract]
Nelson, A., Howe, C., Nguyen, T., Seibel, M., Baxter, R., Handelsman, D., Kazlauskas, R., Ho, K. Erythropoietin administration does not influence the GH--IGF axis or makers of bone turnover in recreational athletes. Clinical endocrinology. 2005; 63:305-9. [Abstract]
Brand-Miller, J., Liu, V., Petocz, P., Baxter, R. The glycemic index of foods influences postprandial insulin-like growth factor-binding protein responses in lean young subjects. The American journal of clinical nutrition. 2005; 82:350-4. [Abstract]
Butt, A., Dickson, K., Jambazov, S., Baxter, R. Enhancement of tumor necrosis factor-alpha-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells. Endocrinology. 2005; 146:3113-22. [Abstract]
Takahashi, M., Papavero, V., Yuhas, J., Kort, E., Kanayama, H., Kagawa, S., Baxter, R., Yang, X., Gray, S., Teh, B. Altered expression of members of the IGF-axis in clear cell renal cell carcinoma. International journal of oncology. 2005; 26:923-31. [Abstract]
Healy, M., Dall, R., Gibney, J., Bassett, E., Ehrnborg, C., Pentecost, C., Rosen, T., Cittadini, A., Baxter, R., Sonksen, P. Toward the development of a test for growth hormone (GH) abuse: A study of extreme physiological ranges of GH-dependent markers in 813 elite athletes in the postcompetition setting. Journal of Clinical Endocrinology and Metabolism. 2005; 90:641-649. [Abstract]
2004
Yan, X., Forbes, B., McNeil, K., Baxter, R., Firth, S. Role of N- and C-terminal residues of insulin-like growth factor (IGF)-binding protein-3 in regulating IGF complex formation and receptor activation. The Journal of biological chemistry. 2004; 279:53232-40. [Abstract]
Scarlett, C., O'leary, M., Kee, A., Nielsen, A., Sevette, A., Baxter, R., Smith, R. A study of parenteral versus enteral nutrition following caecal ligation and puncture in the rat: Influence on survival and tissue protein turnover. Clinical nutrition (Edinburgh, Lothian). 2004; 23:1135-45. [Abstract]
Mesotten, D., Wouters, P., Peeters, R., Hardman, K., Holly, J., Baxter, R., Van den Berghe, G. Regulation of the somatotropic axis by intensive insulin therapy during protracted critical illness. The Journal of clinical endocrinology and metabolism. 2004; 89:3105-13. [Abstract]
Payet, L., Firth, S., Baxter, R. The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers. The Journal of clinical endocrinology and metabolism. 2004; 89:2382-9. [Abstract]
Butt, A., Martin, J., Dickson, K., McDougall, F., Firth, S., Baxter, R. Insulin-like growth factor binding protein-3 expression is associated with growth stimulation of T47D human breast cancer cells: the role of altered epidermal growth factor signaling. The Journal of clinical endocrinology and metabolism. 2004; 89:1950-6. [Abstract]
Schedlich, L., O'Han, M., Leong, G., Baxter, R. Insulin-like growth factor binding protein-3 prevents retinoid receptor heterodimerization: implications for retinoic acid-sensitivity in human breast cancer cells. Biochemical and biophysical research communications. 2004; 314:83-8. [Abstract]
2003
Mesotten, D., Van den Berghe, G., Liddle, C., Coulter, S., McDougall, F., Baxter, R., Delhanty, P. Growth hormone modulation of the rat hepatic bile transporter system in endotoxin-induced cholestasis. Endocrinology. 2003; 144:4008-17. [Abstract]
Butt, A., Dickson, K., McDougall, F., Baxter, R. Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo. The Journal of biological chemistry. 2003; 278:29676-85. [Abstract]
Payet, L., Wang, X., Baxter, R., Firth, S. Amino- and carboxyl-terminal fragments of insulin-like growth factor (IGF) binding protein-3 cooperate to bind IGFs with high affinity and inhibit IGF receptor interactions. Endocrinology. 2003; 144:2797-806. [Abstract]
Frystyk, J., Nyholm, B., Skjaerbaek, C., Baxter, R., Schmitz, O., Ørskov, H. The circulating IGF system and its relationship with 24-h glucose regulation and insulin sensitivity in healthy subjects. Clinical endocrinology. 2003; 58:777-84. [Abstract]
Schedlich, L., Nilsen, T., John, A., Jans, D., Baxter, R. Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation. Endocrinology. 2003; 144:1984-93. [Abstract]
Srinivasan, S., Waters, M., Rowland, J., Baxter, R., Verge, C. Hyperinsulinism and overgrowth without obesity. Archives of disease in childhood. 2003; 88:332-4. [Abstract]
Gunton, J., Delhanty, P., Takahashi, S., Baxter, R. Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. The Journal of clinical endocrinology and metabolism. 2003; 88:1323-32. [Abstract]
Martin, J., Weenink, S., Baxter, R. Insulin-like growth factor-binding protein-3 potentiates epidermal growth factor action in MCF-10A mammary epithelial cells. Involvement of p44/42 and p38 mitogen-activated protein kinases. The Journal of biological chemistry. 2003; 278:2969-76. [Abstract]
Le Roith, D., Zumkeller, W., Baxter, R. Insulin-like Growth Factor Receptor Signalling. Netherlands: Kluwer, 2003.
Ehrnborg, C., Lange, K., Dall, R., Christiansen, J., Lundberg, P., Baxter, R., Boroujerdi, M., Bengtsson, B., Healey, M., Pentecost, C., Longobardi, S., Napoli, R., Rosén, T., , G. The growth hormone/insulin-like growth factor-I axis hormones and bone markers in elite athletes in response to a maximum exercise test. The Journal of clinical endocrinology and metabolism. 2003; 88:394-401. [Abstract]
Fanayan, S., Baxter, R. Functional relationships between transforming growth factor-beta and the insulin-like growth factor binding proteins. In: Insulin-Like Growth Factors. New York: Kluwer Academic/Plenum Publishers 2003. p. 281-293.
2002
Kong, S., Baxter, R., Delhanty, P. Age-dependent regulation of the acid-labile subunit in response to fasting-refeeding in rats. Endocrinology. 2002; 143:4505-12. [Abstract]
Mesotten, D., Delhanty, P., Vanderhoydonc, F., Hardman, K., Weekers, F., Baxter, R., Van Den Berghe, G. Regulation of insulin-like growth factor binding protein-1 during protracted critical illness. The Journal of clinical endocrinology and metabolism. 2002; 87:5516-23. [Abstract]
Firth, S., Baxter, R. Cellular actions of the insulin-like growth factor binding proteins. Endocrine reviews. 2002; 23:824-54. [Abstract]
Kong, S., Firth, S., Baxter, R., Delhanty, P. Regulation of the acid-labile subunit in sustained endotoxemia. American journal of physiology. Endocrinology and metabolism. 2002; 283:E692-701. [Abstract]
Kodama, Y., Baxter, R., Martin, J. Insulin-like growth factor-I inhibits cell growth in the a549 non-small lung cancer cell line. American journal of respiratory cell and molecular biology. 2002; 27:336-44. [Abstract]
Butt, A., Fraley, K., Firth, S., Baxter, R. IGF-binding protein-3-induced growth inhibition and apoptosis do not require cell surface binding and nuclear translocation in human breast cancer cells. Endocrinology. 2002; 143:2693-9. [Abstract]
Donaghy, A., Delhanty, P., Ho, K., Williams, R., Baxter, R. Regulation of the growth hormone receptor/binding protein, insulin-like growth factor ternary complex system in human cirrhosis. Journal of hepatology. 2002; 36:751-8. [Abstract]
Delhanty, P., Mesotten, D., McDougall, F., Baxter, R. Growth hormone rapidly induces resistin gene expression in white adipose tissue of spontaneous dwarf (SDR) rats. Endocrinology. 2002; 143:2445-8. [Abstract]
Firth, S., McDougall, F., McLachlan, A., Baxter, R. Impaired blockade of insulin-like growth factor I (IGF-I)-induced hypoglycemia by IGF binding protein-3 analog with reduced ternary complex-forming ability. Endocrinology. 2002; 143:1669-76. [Abstract]
Van den Berghe, G., Baxter, R., Weekers, F., Wouters, P., Bowers, C., Iranmanesh, A., Veldhuis, J., Bouillon, R. The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. Clinical endocrinology. 2002; 56:655-69. [Abstract]
Fanayan, S., Firth, S., Baxter, R. Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling. The Journal of biological chemistry. 2002; 277:7255-61. [Abstract]
Baxter, R., Meka, S., Firth, S. Molecular distribution of IGF binding protein-5 in human serum. The Journal of clinical endocrinology and metabolism. 2002; 87:271-6. [Abstract]
2001
Baxter, R. Changes in the IGF-IGFBP axis in critical illness. Best practice & research. Clinical endocrinology & metabolism. 2001; 15:421-34. [Abstract]
Sevette, A., Kee, A., Carlsson, A., Baxter, R., Smith, R. Parenteral nutrition with lipid or glucose suppresses liver growth and response to GH in adolescent male rats. American journal of physiology. Endocrinology and metabolism. 2001; 281:E1063-72. [Abstract]
Baxter, R. What is the significance of IGF-binding protein-3 proteolysis in the circulation?. The Journal of clinical endocrinology and metabolism. 2001. p. 5087-8. [Abstract]
van den Berghe, G., Weekers, F., Baxter, R., Wouters, P., Iranmanesh, A., Bouillon, R., Veldhuis, J. Five-day pulsatile gonadotropin-releasing hormone administration unveils combined hypothalamic-pituitary-gonadal defects underlying profound hypoandrogenism in men with prolonged critical illness. The Journal of clinical endocrinology and metabolism. 2001; 86:3217-26. [Abstract]
Baxter, R. Signalling pathways involved in antiproliferative effects of IGFBP-3: a review. Molecular pathology : MP. 2001; 54:145-8. [Abstract]
Firth, S., Clemmons, D., Baxter, R. Mutagenesis of basic amino acids in the carboxyl-terminal region of insulin-like growth factor binding protein-5 affects acid-labile subunit binding. Endocrinology. 2001; 142:2147. [Abstract]
Galanis, M., Firth, S., Bond, J., Nathanielsz, A., Kortt, A., Hudson, P., Baxter, R. Ligand-binding characteristics of recombinant amino- and carboxyl-terminal fragments of human insulin-like growth factor-binding protein-3. The Journal of endocrinology. 2001; 169:123-33. [Abstract]
Delhanty, P., Scott, C., Babu, S., Baxter, R. Acid-labile subunit regulation during the early stages of liver regeneration: implications for glucoregulation. American journal of physiology. Endocrinology and metabolism. 2001; 280:E287-95. [Abstract]
Baxter, R. Inhibition of the insulin-like growth factor (IGF)-IGF-binding protein interaction. Hormone research. 2001; 55 Suppl 2:68-72. [Abstract]
Ranke, M., Feldt-Rasmussen, U., Bang, P., Baxter, R., Camacho-Hübner, C., Clemmons, D., Juul, A., Orskov, H., Strasburger, C. How should insulin-like growth factor I be measured? A consensus statement. Hormone research. 2001; 55 Suppl 2:106-9. [Abstract]
2000
Twigg, S., Hardman, K., Baxter, R. A purified bovine serum albumin preparation contains an insulin-like growth factor (IGF) binding protein-3 fragment that forms ternary complexes selectively with IGF-II and the acid-labile subunit. Growth Hormone & IGF Research. 2000; 10:215-223.
Fanayan, S., Firth, S., Butt, A., Baxter, R. Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta) and the type II TGF-beta receptor. Journal of Biological Chemistry. 2000; 275:39146-39151.
Twigg, S., Kiefer, M., Zapf, J., Baxter, R. A central domain binding site in insulin-like growth factor binding protein-5 for the acid-labile subunit. Endocrinology. 2000; 141:454-457.
Van den Berghe, G., Baxter, R., Weekers, F., Wouters, P., Bowers, C., Veldhuis, J. A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness. Journal of Clinical Endocrinology and Metabolism. 2000; 85:183-192.
Baxter, R., Butt, A., Schedlich, L., Martin, J. Antiproliferative and pro-apoptotic activities of insulin-like growth factor-binding protein-3. Growth Hormone & IGF Research. 2000; Supplement A:S10-S11.
Bond, J., Meka, S., Baxter, R. Binding characteristics of pro-insulin-like growth factor-II from cancer patients: binary and ternary complex formation with IGF binding proteins-1 to -6. Journal of Endocrinology. 2000; 165:253-260.
Salahifar, H., Firth, S., Baxter, R., Martin, J. Characterization of an amino-terminal fragment of insulin-like growth factor binding protein-3 and its effects in MCF-7 breast cancer cells. Growth Hormone & IGF Research. 2000; 10:367-377.
Salahifar, H., Baxter, R., Martin, J. Differential regulation of insulin-like growth factor-binding protein-3 protease activity in MCF-7 breast cancer cells by estrogen and transforming growth factor-beta1. Endocrinology. 2000; 141:3104-3110.
Kam, G., Leung, K., Baxter, R., Ho, K. Estrogens exert route- and dose-dependent effects on insulin-like growth factor (IGF)-binding protein-3 and the acid-labile subunit of the IGF ternary complex. Journal of Clinical Endocrinology and Metabolism. 2000; 85:1918-1922.
Baxter, R. Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities. American Journal of Physiology-Endocrinology and Metabolism. 2000; 278:E967-E976.
Butt, A., Firth, S., King, M., Baxter, R. Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells. Journal of Biological Chemistry. 2000; 275:39174-39181.
Baxter, R., Svejkar, M., Khosravi, M., Bennett, G., Hardman, K., Senese, A., Mistry, J., Walton, P., Quarmby, V. Measurement of the acid-labile subunit of the insulin-like growth factor binding protein complex in human serum: a comparison of four immunoassays. Journal of Endocrinology. 2000; 165:271-279.
Schedlich, L., Le Page, S., Firth, S., Briggs, L., Jans, D., Baxter, R. Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit. Journal of Biological Chemistry. 2000; 275:23462-23470.
Laursen, T., Flyvbjerg, A., Jorgensen, J., Baxter, R., Christiansen, J. Stimulation of the 150-kilodalton insulin-like growth factor-binding protein-3 ternary complex by continuous and pulsatile patterns of growth hormone (GH) administration to GH-deficient patients. Journal of Clinical Endocrinology and Metabolism. 2000; 85:4310-4314.
Dall, R., Longobardi, S., Ehrnborg, C., Keay, N., Rosen, T., Jorgensen, J., Cuneo, R., Boroujerdi, M., Cittadini, A., Napoli, R., Christian sen, J., Bengtsson, B., Sacca, L., Baxter, R., Basset, E., Sonksen, P. The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. Journal of Clinical Endocrinology and Metabolism. 2000; 85:4193-4200.
Coverley, J., Martin, J., Baxter, R. The effect of phosphorylation by casein kinase 2 on the activity of insulin-like growth factor-binding protein-3. Endocrinology. 2000; 141:564-570.